The point of present examination was to investigate the anti-anxiety activity of hydroalcoholic extracts of Tradescantia spathacea utilizing different animal models (elevated plus maze, open field test, light and dark test and social interaction test) of anxiety in mice. Diazepam (0.5 mg/kg) was utilized as the standard and measurement of hydroalcoholic extract of T. spathacea (50, 100 and 200 mg/kg) was chosen according to OECD rules. Results recommended that concentrate of T. spathacea at 100 and 200 mg/kg dose produced anti-anxiety effects almost similar to diazepam and at 50 mg/kg dosage did not create against anti-anxiety activity on any of the paradigm used. Additionally ponders are expected to recognize the anxiolytic mechanism(s) and the phytoconstituents responsible for the observed central effects of the hydroalcoholic extract of T. spathacea.
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